Scientific Research
IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.
Preclinical Research
May 2019 | International Journal of Pharmaceutics
Drug stability and product performance characteristics of a dapivirine-releasing vaginal ring under simulated real-world conditions
Murphy DJ, McCoy CF, Boyd P, Derrick T, Spence P, Devlin B, Malcolm K. International Journal of Pharmaceutics. 11 May 2019: epub ahead of print. doi.org/10.1016/j.ijpharm.2019.05.027
April 2019 | Pharmaceutics
Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis
Yang H, Li J, Patel SK, Palmer KE, Devlin B, Rohan LC. Pharmaceutics 11, no. 4(16 April 2019): 184
April 2019 | International Journal of Pharmaceutics
Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES
McBride JW, Malcolm RK, Dias N, Cameron D, Offord RE, Hartley O, Kett VL, Devlin B, Boyd P. International Journal of Pharmaceutics. 15 Apr 2019: epub ahead of print. doi.org/10.1016/j.ijpharm.2019.04...
August 2017 | Journal of Pharmaceutical Sciences
Packing Polymorphism of Dapivirine and Its Impact on the Performance of a Dapivirine-Releasing Silicone Elastomer Vaginal Ring
McCoy SF, Murphy DJ, Boyd P, Derrick T, Spence P, Devlin B, Malcolm RK. Journal of Pharmaceutical Sciences. 106, no. 8 (Aug 2017): 2015-25.
September 2016 | International Journal of Pharmaceutics
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
Boyd P, Fetherston SM, McCoy CF, Major I, Murphy DJ, Kumar S, Holt J, Brimer A, Blanda W, Devlin B, Malcolm RK. International Journal of Pharmaceutics. 511, no. 1 (10 Sept 2016): 619-629.
July 2016 | European Journal of Pharmaceutics and Biopharmaceutics
Development of a multi-layered vaginal tablet containing dapivirine, levonorgestrel and acyclovir for use as a multipurpose prevention technology
McConville C, Major I, Devlin B, Brimer A. European Journal of Pharmaceutics and Biopharmaceutics. 104 (Jul 2016): 171-9.
April 2016 | AIDS
Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates
Herrera C, Armanasco, N, García-Pérez J, Ziprin P, Olejniczak N, Alcamí J, Nuttall J, Shattock RJ. AIDS. 30, no. 7 (24 Apr 2016):1015-1025.
March 2016 | AIDS Research and Human Retroviruses
Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues
Fletcher P, Herrera C, Armanasco N, Nuttall J, Shattock RJ. AIDS Research and Human Retroviruses. 32, no. 4(Mar 2016): 334-8.
March 2016 | Journal of Controlled Release
Controlling levonorgestrel binding and release in a multi-purpose prevention technology vaginal ring device
Murphy DJ, Boyd P, McCoy CF, Kumar S, Holt JDS, Blanda W, Brimer AN, Malcolm RK. Journal of Controlled Release. 226 (28 Mar 2016): 138-147.
November 2015 | Pharmaceutical Research
Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention
Dezzutti CS, Yandura S, Wang L, Moncla B, Teeple EA, Devlin B, Nuttall J, Brown ER, Rohan LC. Pharmaceutical Research. 32, no. 11 (Nov 2015):3768-81.