Scientific Research

IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.

Clinical Research

August 2011 | PLoS ONE

HIV Prevalence and Incidence among Sexually Active Females in Two Districts of South Africa to Determine Microbicide Trial Feasibility.

Nel A., Louw C., Hellstrom E., Braunstein SL., Treadwell I., Marais M., de Villiers M., Hugo J., Paschke I., Andersen C., van de Wijgert J. PLoS ONE 6, no. 8 (August 2011): e21528.

August 2011 | Journal of Women's Health

Acceptability of Vaginal Film, Soft-Gel Capsule, and Tablet as Potential Microbicide Delivery Methods Among African Women.

Nel A., Mitchnick L., Risha P., Muungo LTM., Norick P. Journal of Women's Health 20, no. 8 (August 2011): 1207-1214.

July 2010 | AIDS Research and Human Retroviruses

Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women.

Nel A.M., Coplan P., Smythe S.C., McCord K., Mitchnick M., Romano J. Accepted for publication in AIDS Research and Human Retroviruses. July 2010

June 2010 | Journal of Acquired Immune Deficiency Syndromes

Pharmacokinetics of two dapivirine vaginal microbicide gels and their safety vs. hydroxyethyl cellulose-based universal placebo gel.

 Nel A., Smythe S., Habibi S., Romano J. Journal of Acquired Immune Deficiency Syndromes. June 2010.  

January 2010 | BMC Infectious Diseases

Association of HIV infection with distribution and viral load of HPV types in Kenya: a survey with 820 female sex workers.

Luchters S.M., Vanden Broeck D., Chersich M.F., Nel A., Delva W., Mandaliya K., Depuydt C.E., Claeys P., Bogers J.P., Temmerman M. BMC Infectious Diseases 10, no. 18 (2010).

August 2009 | Journal of Acquired Immune Deficiency Syndromes

Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women.

Nel A., Smythe S., Young K., Malcolm K., McCoy C., Rosenberg Z., Romano J. Journal of Acquired Immune Deficiency Syndromes 51, no. 4 (August 2009): 416-23

July 2009 | AIDS

Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy HIV-negative women.

Nel A.M., Coplan P., van de Wijgert J.H., Kapiga S.H., von Mollendorf C., Geubbels E., Vyankandondera J., Rees H.V., Masenga G., Kiwelu I., Moyes J., Smythe S.C. AIDS 23, no. 12 (July 2009): 1531-8.

May 2009 | AIDS Research and Human Retroviruses

Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring.

Romano J., Variano B., Coplan P., Van Roey J., Douville K., Rosenberg Z., Temmerman M., Verstraelen H., Van Bortel L., Weyers S., Mitchnick M. AIDS Research and Human Retroviruses 25, no. 5 (2009):...

October 2008 | The Microbicide Quarterly

Modeling the social context of microbicide use.

Simons-Rudolph A.P., Woodsong C., Koo H.P. The Microbicide Quarterly 6, no. 4 (2008): 1-11.

April 2008 | Sexually Transmitted Diseases

A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor.

Schwartz J.L., Kovalevsky G., Lai J.J., Ballagh S.A., McCormick T., Douville K., Mauck C.K., Callahan M.M. Sexually Transmitted Diseases 35, no. 4 (2008): 414-9.