IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.
June 2012 | Pharmaceutical Research
Polymeric Nanoparticles Affect the Intracellular Delivery, Antiretroviral Activity and Cytotoxicity of the Microbicide Drug Candidate Dapivirine.
das Neves J, Michiels J, Arien KK, Vanham G, Amiji M, Bahia MF, Sarmento B. Pharmaceutical Research. 29, no. 6 (June 2012): 1468-84. Epub 10 November 2011.
April 2012 | Journal of Pharmaceutical Sciences
Development of a Combination Microbicide Gel Formulation Containing IQP-0528 and Tenofovir for the Prevention of HIV Infection
Ham AS, Ugaonkar SR, Shi L, Buckheit KW, Lakougna H, Nagaraja U, Gwozdz G, Goldman L, Kiser PF, Buckheit RW Jr. Journal of Pharmaceutical Sciences. 101, no. 4 (April 2012):1423-35. Epub 6 Jan 2012.
January 2012 | Antimicrobial Agents and Chemotherapy
Pharmacokinetics of Tenofovir following Intravaginal and Intrarectal Administration of Tenofovir Gel to Rhesus Macaques.
Nuttall J, Kashuba A, Wang R, White N, Allen P, Robert J, Romano J. Antimicrobial Agents and Chemotherapy. 56, no. 1 (January 2012):103-9. Epub 10 October 2011.
June 2010 | Journal of Pharmaceutical and Biomedical Analysis
Development and validation of a rapid reversed-phase HPLC method for the determination of the non-nucleoside reverse transcriptase inhibitor dapivirine from polymeric nanoparticles.
das Neves J, Sarmento B, Amiji MM, Bahia MF. Journal of Pharmaceutical and Biomedical Analysis. 52, no. 2 (5 June 2010):167-72. Epub 2010 Jan 15.
March 2010 | International Journal of Pharmaceutics
Freeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: optimization by an artificial neural network.
Woolfson A.D., Umrethia M.L., Kett V.L., Malcolm R.K. International Journal of Pharmaceutics 388, no.1-2 (2010):136-143.
February 2010 | European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences
Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir.
Johnson T.J., Gupta K.M., Fabian J., Albrights T.H., Kiser P.F. European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences 39, no. 4 (2010):...
February 2009 | Antimicrobial Agents and Chemotherapy
Inhibition of HIV-1 infection by the candidate microbicide, dapivirine, a nonnucleoside reverse transcriptase inhibitor.
Fletcher P., Harman S., Azijn H., Armanasco N., Manlow P., Perumal D., de Bethune M-P., Nuttall J., Romano J., Shattock R. Antimicrobial Agents and Chemotherapy 53, no. 2 (2009):487-95.
March 2008 | Antimicrobial Agents and Chemotherapy
Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C] dapivirine for 7 days.
Nuttall J.P., Thake D.C., Lewis M.G., Ferkany J.W., Romano J.W., Mitchnick M.A. Antimicrobial Agents and Chemotherapy 52, no. 3(2008) :909-14.
February 2005 | Protein Expression and Purification
Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development.
Colleluori D.M., Tien D., Kang F., Pagliei T., Kuss R., McCormick T., Watson K., McFadden K., Chaiken I., Buckheit R.W., Jr, Romano J.W. Protein Expression and Purification 39, no. 2 (2005): 229-36.
February 2019 | Antimicrobial Agents and Chemotherapy
Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women Using the Dapivirine Vaginal Ring
Noguchi LM, Hoesley C, Kelly C, Scheckter R, Bunge K, Nel A, Marzinke MA, Hendrix CW, Dezzutti CS, Hillier SL, Bogen DL, Piper JM, Beigi RH. Antimicrobial Agents and Chemotherapy. 63, vol. 3 (2019...