Scientific Research

IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.

Clinical Research

March 2016 | PLOS ONE

Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa

Nel A, Bekker LG, Bukusi E, Hellstrӧm, Kotze P, Louw C, Martinson F, Masenga G, Montgomery E, Ndaba N, van der Straten A, van Niekerk N, Woodsong C. PLOS ONE. 10 Mar 2016, doi: 10.1371/journal.pone....

November 2015 | Journal of Acquired Immune Deficiency Syndromes

A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of a novel dapivirine vaginal film

Bunge KE, Dezzutti CS, Rohan LC, Hendrix CW, Marzinke MA, Richardson-Harman N, Moncla BJ, Devlin B, Meyn LA, Spiegel HML, Hillier SL. Journal of Acquired Immune Deficiency Syndromes. Epub 2015 Nov 11.

May 2015 | Journal of Acquired Immune Deficiency Syndromes

Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: a Double-Blind Randomized Trial

Chen BA, Panther L, Marzinke MA, Hendrix CW, Hoesley CJ, van der Straten A, Husnik MJ, Soto-Torres L, Nel A, Johnson S, Richardson-Harman, Rabe LK, Dezzutti CS. Journal of Acquired Immune Deficiency...

October 2014 | Journal of AIDS & Clinical Research

Pharmacokinetics and Safety Assessment of Anti-HIV Dapivirine Vaginal Microbicide Rings with Multiple Dosing

Nel AM, Haazen W, Nuttall JP, Romano JW, Mesquita PMM, Herold BC, Rosenberg ZF, van Niekerk N. Journal of AIDS & Clinical Research. 5 (3 Oct 2014):355.

September 2014 | Journal of the International AIDS Society

Community and research staff collaboration for development of materials to inform microbicide study participants in Africa

Woodsong C, Mutsambi JM, Ntshele S, Modikoe P. JIAS. 17(Suppl 2):19156.

June 2014 | AIDS.

A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women

Nel A, Haazen W, Nuttall J, Romano J, Rosenberg Z, van Niekerk N. AIDS. 28, no. 10 (June 19, 2014):1479-87.

February 2014 | AIDS Research and Human Retroviruses

A Randomized Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures (MTN 012/IPM 010)

Cranston RD, Hoesley C, Carballo-Diéguez A, Hendrix CW, Husnik M, Levy L, Hall W, Soto-Torres L, Nel AM. AIDS Research and Human Retroviruses. 30, no. 2 (2014 Feb):184-9. Epub 2013 Oct 26. 

April 2013 | Journal of the International AIDS Society

Microbicide clinical trial adherence: insights for introduction

Woodsong C, MacQueen K, Amico KR, Friedland B, Gafos M, Mansoor L, Tolley E, McCormack S. Journal of the International AIDS Society. 16 (8 Apr 2013):18505.

October 2012 | AIDS and Behavior

High Acceptability of a Vaginal Ring Intended as a Microbicide Delivery Method for HIV Prevention in African Women.

van der Straten A, Montgomery ET, Cheng H, Wegner L, Masenga G, von Mollendorf C, Bekker L, Ganesh S, Young K, Romano J, Nel A, Woodsong C. AIDS and Behavior. 16, no. 7 (October 2012): 1775-86. Epub...

October 2012 | AIDS and Behavior

Vaginal Ring Adherence in Sub-Saharan Africa: Expulsion, Removal, and Perfect Use.

Montgomery ET, van der Straten A, Cheng H, Wegner L, Masenga G, von Mollendorf C, Bekker L, Ganesh S, Young K, Romano J, Nel A, Woodsong C. AIDS and Behavior. 16, no. 7 (October 2012):1787-98. Epub...

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