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Pharmaceutical Company Partners

Since 2004, IPM has obtained six non-exclusive, royalty-free license agreements from pharmaceutical companies to develop, manufacture and distribute eight antiretroviral (ARV) products as microbicides in developing countries.

These royalty-free licenses ensure that any new product will be available at little or no cost to women in developing countries where incidence of HIV is especially high.

IPM Products in Development
Compound License Mechanism of action IPM development stage
Dapivirine Janssen R&D Ireland (previously Tibotec) NNRTI: Reverse transcription
  • Phase I/II clinical (dapivirine ring and dapivirine gel)
  • Initiation of safety and efficacy studies in 2012 (dapivirine ring)
L167, L872, L882 Merck CCR5: Cell Attachment
  • Preclinical
Tenofovir Gilead NRTI: Reverse transcription 
  • Preclinical* (maraviroc-tenofovir film)
BMS793 BMS gp120: Cell attachment
  • Preclinical (vaginal tablet)
Maraviroc Viiv Healthcare CCR5: Cell Attachment
  • Phase I clinical (dapivirine-maraviroc combination ring and gel)
  • Preclinical (maraviroc-tenofovir combination film)
L-644 peptide Merck gp41: Cell fusion
  • Early preclinical

* Compound is in different stages of development by other organizations

IPM continually seeks opportunities to work with pharmaceutical companies and other public and private sector research-based organizations and institutions to collaborate on developing promising microbicide and other HIV prevention products.

IPM pharmaceutical partners
Bristol-Myers Squibb
Bristol-Myers Squibb, USA		 Gilead
Gilead Sciences, Inc., USA		 Merck
Merck & Co., Inc., USA

Janssen R&D Ireland

Janssen R&D Ireland

Viiv Healthcare

Viiv Healthcare