IPM 100.1

Details

Protocol Title:  A Two-Part, Cross-Sectional and Prospective, Observational Study to Estimate HIV Incidence among Sexually Active, Adult Females

Status:  Ongoing

Description

IPM 100.1 is a cross-sectional and prospective cohort study aimed at estimating HIV incidence (rate of new infections) among sexually active women, ages 18 to 40, with two primary objectives:

  1. determine HIV incidence in preparation for future HIV microbicide efficacy trials
  2. detect acute HIV infection in study participants  

IPM 100.1 is being conducted in Kenya and Zimbabwe, and will include approximately 800 participants in the cross-sectional component. Additionally, 300 of these participants who are HIV negative will be enrolled into a prospective cohort study for a 12-month follow-up period with HIV infection as the primary endpoint.

Participating Research Centers

  • Kenya Medical Research Institute (KEMRI) — Suba, Kenya
  • Africa University Clinical Research Centre (AUCRC) — Mutare, Zimbabwe