Protocol Title: A Two-Cohort, Open-Label, Randomised, Three-Period Crossover Trial in Healthy HIV-Negative Women to Assess the Effect of Menses and Tampon Use on the Pharmacokinetics of Dapivirine, Delivered by Dapivirine Vaginal Ring-004, Containing 25mg of Dapivirine
IPM 035 is a clinical trial designed to assess the effects of menses, and of tampon use during menses, on the local and systemic pharmacokinetics of the dapivirine ring when used by HIV-negative women over a period of 28 days.
- ClinicalTrials ID: NCT02858024
Participating Research Centers
- SGS Life Science Services — Antwerp, Belgium
Publications, presentations or other scientific data
- Nel et al. Effect of menses and tampon use on the pharmacokinetics of Dapivirine Vaginal Ring [poster presentation]. IAS 2017. See abstract.