Partners & Sponsors
IPM has partnered with a variety of institutions to advance the dapivirine ring from concept to late-stage clinical trials in just seven years, each bringing complementary resources and scientific ingenuity to the ring licensure program:
Microbicide Trials Network (MTN): Funded by the US National Institutes of Health, MTN is a worldwide collaborative clinical trials network focused on preventing the sexual transmission of HIV. Given the dapivirine ring’s promise as a microbicide, MTN partnered with IPM to advance the ring into parallel late-stage clinical trials. MTN conducted the ASPIRE study across 15 sites in Malawi, South Africa, Uganda and Zimbabwe.
Research center partners: IPM partners with local research centers in Africa to conduct clinical studies. The following research centers participated in The Ring Study:
- Madibeng Centre for Research, Brits, North-West, South Africa
- Qhakaza Mbokodo, Ladysmith, KwaZulu-Natal, South Africa
- Maternal, Adolescent and Child Health, (MatCH), Edendale, KwaZulu-Natal, South Africa
- Prevention of HIV/AIDS Project (PHIVA), Pinetown, KwaZulu-Natal, South Africa
- Desmond Tutu HIV Foundation, Masiphumelele, South Africa
- Ndlovu Medical Centre, Elandsdoorn, Limpopo, South Africa
- MRC/UVRI Uganda Research Unit on AIDS, Masaka, Uganda
Janssen Sciences Ireland UC: IPM began developing dapivirine for use as a microbicide in 2004 through a royalty-free licensing agreement with Janssen Sciences Ireland UC (previously Tibotec Pharmaceutials), one of the Janssen pharmaceutical companies of Johnson & Johnson. This license has since been expanded to a worldwide rights agreement.
QPharma: A Sweden-based contract developer and pharmaceuticals manufacturer with 35 years experience, QPharma is manufacturing the dapivirine vaginal rings for the licensure program using highly specialized equipment.
Donors: IPM’s work to date has been supported by governments, multilateral organizations and foundations including: Belgian Development Cooperation, Canadian International Development Agency, Flanders Department of Foreign Affairs, Federal Ministry for Economic Cooperation and Development of Germany, Irish Aid, Ministry for Foreign Affairs of Sweden, Ministry of Foreign Affairs of Denmark, Ministry of Foreign Affairs of France, Ministry of Foreign Affairs and Cooperation of Spain, Ministry of Foreign Affairs of the Netherlands, Norwegian Agency for Development Cooperation (Norad), Norwegian Ministry of Foreign Affairs, Swedish International Development Agency, United Kingdom Department for International Development (DFID), and the American people through the United States Agency for International Development (USAID) through the President’s Emergency Plan for AIDS Relief (PEPFAR); European Commission, World Bank and United Nations Population Fund; and Bill and Melinda Gates Foundation, Magee-Womens Research Institute and Foundation, MAC AIDS Fund, OPEC Fund for International Development and Rockefeller Foundation. View IPM’s donor list.