Scientific Research

IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.

Clinical Research

October 2021 | AIDS Education and Prevention

Acceptability of a Dapivirine Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-033 Study)

Bauermeister JA, Tingler RC, Johnson S, Macagna N, Lucas J, Dominguez-Islas C, Szydlo D, Ngo J, Jacobson CE, Kramzer L, Singh D, Dezzutti CS, Ayudhya RPKN, Piper J, Devlin B, Hendrix CW, Ho K. AIDS...

September 2021 | AIDS Research and Human Retroviruses

A Randomized, Double Blind, Placebo-Controlled, Phase 1 Safety and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative Adults (MTN-026)

Cranston RD, Brown E, Bauermeister J, Dunne EF, Hoesley C, Ho K, Johnson S, Lucas J, Dominguez-Islas C, Gundacker H, Peda M, Jacobson CE, Kramzer L, Singh D, Dezzutti CS, Ayudhya RPKN, Brand RM, Wang...

August 2021 | AIDS Research and Human Retroviruses

A Randomized, Open Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study)

McGowan IM, Chawki S, Hendrix CW, Anton PA, Marzinke MA, Brand RM, Engstrom JC, Rohan LC, Abebe KZ, Richardson-Harman N, Siegel A, Rineheart A, Steytler J, Stall R, Spiegel H, Chen B, Achilles SL,...

June 2021 | Journal of the International AIDS Society

Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States

Liu AY, Islas CD, Gundacker H, Neradilek B, Hoesley C, van der Straten A, Hendrix CW, Beamer M, Jacobson CE, McClure T, Harrell T, Bunge K, Devlin B, Nuttall J, Spence P, Steytler J, Piper JM,...

February 2021 | The Lancet HIV

Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study

Nel A, van Niekerk N, Van Baelen B, Malherbe M, Mans W, Carter A, Steytler J, van der Ryst E, Craig C, Louw C, Gwetu T, Mabude Z, Kotze P, Moraba R, Tempelman H, Gill K, Kusemererwa S, Bekker L-G,...

February 2021 | The Lancet HIV

Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study

Baeten JM, Palanee-Phillips T, Mgodi NM, Mayo AJ, Szydlo DW, Ramjee G, Mirembe BG, Mhlanga F, Hunidzarira P, Mansoor LE, Siva S, Govender V, Makanani B, Naidoo L, Singh N, Nair G, Chinula L, Parikh...

May 2020 | JAIDS

Performance and Acceptability of the FC2 Female Condom® when Used With and Without a Silicone Placebo Vaginal Ring – A Randomized, Crossover Trial

Nel A, Malherbe M, van Niekerk N, Beksinska M, Greener R, Smit J, Frezieres R, Walsh T. JAIDS. 2020 May 20. doi: 10.1097/QAI.0000000000002408. [Epub ahead of print]

May 2020 | JAIDS

Performance of Male Condoms when Used With and Without a Silicone Placebo Vaginal Ring – A Randomized, Crossover Trial

Nel A, Malherbe M, van Niekerk N, Beksinska M, Greener R, Smit J, Frezieres R, Walsh T. JAIDS. 2020 May 4. doi: 10.1097/QAI.0000000000002397. [Epub ahead of print]

February 2020 | JAIDS

Phase IIa Safety Study of a Vaginal Ring Containing Dapivirine in Adolescent Young Women

Bunge KE, Levy L, Szydlo DW, Zhang J, Gaur AH, Reirden D, Mayer KH, Futterman D, Hoesley C, Hillier SL, Marzinke MA, Hendrix CW, Gorbach PM, Wilson CM, Soto-Torres L, Kapogiannis B, Nel A, Squires KE...

August 2019 | AIDS

Social Harms in Female-INITIATED hiv prevention method RESEARCH: state of the evidence

Montgomery ET, Roberts ST, Nel A, Malherbe M, Torjesen K, Bunge K, et al. AIDS. 2019 Nov 15; 33(14): 2237-2244.

Pages