IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, author, journal name or year published.
Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial
Dezzutti CS, Richardson-Harman N, Rohan L, Marzinke MA, Hoesley CJ, Panther L, Johnson S, Nuttall JP, Nel A, Chen BA. Medicine 95, no. 8 (2016 Jul): e4174. doi: 10.1097/MD.0000000000004174.
Post-use assay of vaginal rings (VRs) as a potential measure of clinical trial adherence
Spence P, Nel A, van Niekerk N, Derrick T, Wilder S, Devlin B. Journal of Pharmaceutical and Biomedical Analysis. 125 (5 Jun 2016): 94-100.
Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa
Nel A, Bekker LG, Bukusi E, Hellstrӧm, Kotze P, Louw C, Martinson F, Masenga G, Montgomery E, Ndaba N, van der Straten A, van Niekerk N, Woodsong C. PLOS ONE. 10 Mar 2016, doi: 10.1371/journal.pone....
A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of a novel dapivirine vaginal film
Bunge KE, Dezzutti CS, Rohan LC, Hendrix CW, Marzinke MA, Richardson-Harman N, Moncla BJ, Devlin B, Meyn LA, Spiegel HML, Hillier SL. Journal of Acquired Immune Deficiency Syndromes. Epub 2015 Nov 11.
Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: a Double-Blind Randomized Trial
Chen BA, Panther L, Marzinke MA, Hendrix CW, Hoesley CJ, van der Straten A, Husnik MJ, Soto-Torres L, Nel A, Johnson S, Richardson-Harman, Rabe LK, Dezzutti CS. Journal of Acquired Immune Deficiency...
Pharmacokinetics and Safety Assessment of Anti-HIV Dapivirine Vaginal Microbicide Rings with Multiple Dosing
Nel AM, Haazen W, Nuttall JP, Romano JW, Mesquita PMM, Herold BC, Rosenberg ZF, van Niekerk N. Journal of AIDS & Clinical Research. 5 (3 Oct 2014):355.
A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women
Nel A, Haazen W, Nuttall J, Romano J, Rosenberg Z, van Niekerk N. AIDS. 28, no. 10 (June 19, 2014):1479-87.
A Randomized Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures (MTN 012/IPM 010)
Cranston RD, Hoesley C, Carballo-Diéguez A, Hendrix CW, Husnik M, Levy L, Hall W, Soto-Torres L, Nel AM. AIDS Research and Human Retroviruses. 30, no. 2 (2014 Feb):184-9. Epub 2013 Oct 26.
High Acceptability of a Vaginal Ring Intended as a Microbicide Delivery Method for HIV Prevention in African Women.
van der Straten A, Montgomery ET, Cheng H, Wegner L, Masenga G, von Mollendorf C, Bekker L, Ganesh S, Young K, Romano J, Nel A, Woodsong C. AIDS and Behavior. 16, no. 7 (October 2012): 1775-86. Epub...
Vaginal Ring Adherence in Sub-Saharan Africa: Expulsion, Removal, and Perfect Use.
Montgomery ET, van der Straten A, Cheng H, Wegner L, Masenga G, von Mollendorf C, Bekker L, Ganesh S, Young K, Romano J, Nel A, Woodsong C. AIDS and Behavior. 16, no. 7 (October 2012):1787-98. Epub...