Scientific Research
IPM researchers publish scientific and technical articles on a variety of topics from product development and clinical trial results to regulatory policy. Scroll through or use the Filtered Search in the left sidebar to locate articles by keyword, research category, drug, journal name or year published.
Preclinical Research
August 2017 | Journal of Pharmaceutical Sciences
Packing Polymorphism of Dapivirine and Its Impact on the Performance of a Dapivirine-Releasing Silicone Elastomer Vaginal Ring
McCoy SF, Murphy DJ, Boyd P, Derrick T, Spence P, Devlin B, Malcolm RK. Journal of Pharmaceutical Sciences. 106, no. 8 (Aug 2017): 2015-25.
September 2016 | International Journal of Pharmaceutics
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
Boyd P, Fetherston SM, McCoy CF, Major I, Murphy DJ, Kumar S, Holt J, Brimer A, Blanda W, Devlin B, Malcolm RK. International Journal of Pharmaceutics. 511, no. 1 (10 Sept 2016): 619-629.
July 2016 | European Journal of Pharmaceutics and Biopharmaceutics
Development of a multi-layered vaginal tablet containing dapivirine, levonorgestrel and acyclovir for use as a multipurpose prevention technology
McConville C, Major I, Devlin B, Brimer A. European Journal of Pharmaceutics and Biopharmaceutics. 104 (Jul 2016): 171-9.
April 2016 | AIDS
Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates
Herrera C, Armanasco, N, García-Pérez J, Ziprin P, Olejniczak N, Alcamí J, Nuttall J, Shattock RJ. AIDS. 30, no. 7 (24 Apr 2016):1015-1025.
March 2016 | AIDS Research and Human Retroviruses
Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues
Fletcher P, Herrera C, Armanasco N, Nuttall J, Shattock RJ. AIDS Research and Human Retroviruses. 32, no. 4(Mar 2016): 334-8.
March 2016 | Journal of Controlled Release
Controlling levonorgestrel binding and release in a multi-purpose prevention technology vaginal ring device
Murphy DJ, Boyd P, McCoy CF, Kumar S, Holt JDS, Blanda W, Brimer AN, Malcolm RK. Journal of Controlled Release. 226 (28 Mar 2016): 138-147.
November 2015 | Pharmaceutical Research
Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention
Dezzutti CS, Yandura S, Wang L, Moncla B, Teeple EA, Devlin B, Nuttall J, Brown ER, Rohan LC. Pharmaceutical Research. 32, no. 11 (Nov 2015):3768-81.
July 2015 | Antimicrobial Agents and Chemotherapy
The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides
Holt JDS, Cameron D, Dias N, Holding J, Muntendam, Oostebring F, Dreier P, Rohan L and Nuttall J. Anitmicrobial Agents and Chemotherapy. 59, no. 7 (July 2015): 3761-3770.
February 2015 | Acta Biomaterialia
Precise engineering of dapivirine-loaded nanoparticles for the development of anti-HIV vaginal microbicides
das Neves J and Sarmento B. Acta Biomaterialia. Epub 17 Feb 2015.
July 2014 | Pharmaceutical Research
Formulation and Characterization of Polymeric Films Containing Combinations of Antiretrovirals (ARVs) for HIV Prevention
Akil A, Agashe H, Dezzutti CS, Moncla BJ, Hillier SL, Devlin B, Shi Y, Uranker K, Rohan LC. Pharmaceutical Research. Epub 31 July 2014.