IPM 024

Details

Protocol Title:  A Double-Blind, Randomized, Placebo-Controlled Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess Delivery of Dapivirine From the Matrix Ring Containing 25mg of Dapivirine

Status:  Completed

Description

IPM 024 is a safety and pharmacokinetic trial that evaluated how a platinum-catalyzed matrix dapivirine vaginal ring delivers drug for 28 consecutive days. Specifically, it assessed the safety and tolerability of the vaginal ring containing dapivirine as compared to the placebo ring.

It also assessed dapivirine concentrations in plasma and vaginal fluids before, during, and after 28 day use of a silicone elastomer matrix vaginal ring containing dapivirine.

The trial took place at one research centre in Belgium among 16 healthy, HIV-negative women.

Participating Research Centers

  • SGS Life Science Services – Antwerp, Belgium

Publications, presentations or other scientific data

  • IPM 024 poster presentation